Details

Autor(en) / Beteiligte

• Green, Jeremy B.A.

Titel

Computational biology: Turing’s lessons in simplicity

Ist Teil von

• Biophysical journal, 2021-10, Vol.120 (19), p.4139-4141

Ort / Verlag

Elsevier Inc

Erscheinungsjahr

2021

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Biophysical modeling of development started with Alan Turing. His two-morphogen reaction-diffusion model was a radical but powerful simplification. Despite its apparent limitations, the model captured real developmental processes that only recently have been validated at the molecular level in many systems. The precision and robustness of reaction-diffusion patterning, despite boundary condition-dependence, remain active areas of investigation in developmental biology.