Details

Autor(en) / Beteiligte

• Botwin, Gregory J.
• Li, Dalin
• Figueiredo, Jane
• Cheng, Susan
• Braun, Jonathan
• McGovern, Dermot P.B.
• Melmed, Gil Y.

Titel

Adverse Events Following SARS-CoV-2 mRNA Vaccination Among Patients with Inflammatory Bowel Disease

Ist Teil von

• The American journal of gastroenterology, 2021-08, Vol.116 (8), p.1746-1751

Erscheinungsjahr

2021

Link zum Volltext

Beschreibungen/Notizen

• Patients with immune-mediated inflammatory diseases (IMID) such as inflammatory bowel disease (IBD) on immunosuppressive and biologic therapies were largely excluded from SARS-CoV-2 mRNA vaccine trials. We thus evaluated post-mRNA vaccination adverse events (AE) in 246 vaccinated adults with IBD participating in a longitudinal vaccine registry. In general, AE frequency was similar to that reported in the general population. AE were more common among younger patients, and those with prior COVID-19. We additionally found that AE were less common in individuals receiving biologic therapy. Those with IBD and other IMID on these commonly prescribed therapies can be reassured that the AE risk is likely not increased, and may be reduced, while on biologics.