Organic letters, 2021-05, Vol.23 (10), p.4078-4082
2021
Details
- Autor(en) / Beteiligte
- Titel
- Short and Modular Synthesis of Substituted 2‑Aminopyrroles
- Ist Teil von
- Organic letters, 2021-05, Vol.23 (10), p.4078-4082
- Ort / Verlag
- United States: American Chemical Society
- Erscheinungsjahr
- 2021
- Link zum Volltext
- Quelle
- Alma/SFX Local Collection
- Beschreibungen/Notizen
- We herein describe a simple and metal-free domino methodology to synthesize 2-aminopyrroles from alkynyl vinyl hydrazides. The domino reaction involves a novel propargylic 3,4-diaza-Cope rearrangement and a tandem isomerization/5-exo-dig N-cyclization reaction. By using this approach, a number of 2-aminopyrroles with diverse substituents have been prepared.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1523-7060eISSN: 1523-7052DOI: 10.1021/acs.orglett.1c01345Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8483442
- Format
- –
- Schlagworte
- Letter