Details

Autor(en) / Beteiligte

• NURROHMAN, Hamid
• HABELITZ, Stefan
• SAEKI, Kuniko
• SADR, Alireza
• GOWER, Laurie B.
• PAZDERNIK, Vanessa
• TAGAMI, Junji
• MARSHALL, Sally J.
• MARSHALL, Grayson W.

Titel

Enhanced silver diamine fluoride therapy using the PILP method —A nanoindentation study

Ist Teil von

• Dental Materials Journal, 2020/11/27, Vol.39(6), pp.1009-1015

Ort / Verlag

Japan: The Japanese Society for Dental Materials and Devices

Erscheinungsjahr

2020

Quelle

MEDLINE

Beschreibungen/Notizen

• The aim of this study was to evaluate the feasibility of applying the polymer-induced liquid-precursor (PILP) method to enhance silver diamine fluoride (SDF) therapy. One hundred forty micrometer deep artificial caries lesions were treated with (A) 38% SDF solution and (B) 38% SDF containing poly-L-aspartic acid (pASP). Changes in the nanomechanical profile across the lesion were evaluated. Hydrated artificial lesions had a low reduced elastic modulus (0.3 GPa) and nanohardness (0.02 GPa) region extending about 100 μm into the lesion, with a gradual linear increase to about 168 μm where the values plateaued to around 18 GPa/1.0 GPa. Topical application of SDF resulted in significantly recovered properties (p<0.001). SDF containing pASP resulted in greater nanomechanical properties compared to SDF alone, showing similar sloped regions up to 96 μm, then SDF alone dropped while SDF containing pASP continued at a modest slope until reaching normal at 144 μm. This nanoindentation study shows enhanced SDF therapy using the PILP method.