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Is the Strongest Level of Medical Evidence Always Required for Guidelines Recommendations?
Ist Teil von
Liver cancer (Basel ), 2021-07, Vol.10 (4), p.394-395
Ort / Verlag
Basel, Switzerland: S. Karger AG
Erscheinungsjahr
2021
Quelle
EZB Electronic Journals Library
Beschreibungen/Notizen
[...]the authors of the article are to be commended for their effort to produce the highest level of evidence to confirm the survival benefit of LT in downstaged HCC. The aim of our comment was not to criticize the study design or its ethical implications but to open the discussion concerning the validity of large prospective cohort studies to change the clinical practice without the need of randomized trials. Conflict of Interest Statement Fabio Piscaglia is an editorial board member of Liver Cancer.