Details

Autor(en) / Beteiligte

• Aboueshia, Mohamed
• Hussein, Mohammad Hosny
• Attia, Abdallah S
• Swinford, Aubrey
• Miller, Peter
• Omar, Mahmoud
• Toraih, Eman Ali
• Saba, Nakhle
• Safah, Hana
• Duchesne, Juan
• Kandil, Emad

Titel

Cancer and COVID-19: analysis of patient outcomes

Ist Teil von

• Future oncology (London, England), 2021-09, Vol.17 (26), p.3499-3510

Ort / Verlag

London, UK: Future Medicine Ltd

Erscheinungsjahr

2021

Beschreibungen/Notizen

• We sought to investigate the outcomes associated with COVID-19 disease in cancer patients. We conducted a retrospective cohort study of laboratory-confirmed COVID-19 patients. Of the 206 patients included, 57 had at least one preexisting malignancy. Cancer patients were older than noncancer patients. Of the 185 discharged cases, cancer patients had a significantly higher frequency of unplanned reintubation (7.1% vs 0.9%, p < 0.049), and required longer hospital stay (8.58 ± 6.50 days versus 12.83 ± 11.44 days, p < 0.002). Regression analysis revealed that obesity and active smoking were associated with an increased risk of mortality. Outcomes in COVID-19 appear to be driven by obesity as well as active smoking, with no difference in mortality between cancer and noncancer patients. In this study, we aimed to investigate how COVID-19 affected cancer patients and whether this altered their survival outcomes. To do this, we examined data from a database of patients who have passed through our institution – a retrospective cohort analysis. Of the 206 patients we included in the study from this database, 57 had at least one preexisting cancer. Cancer patients tended to be older than noncancer patients. Of the 185 discharged patients, cancer patients required longer hospital stays, but there was no difference in mortality. Disease complications and intensive care unit admission with obesity and active smoking put patients in our cohort at increased risk of death. To conclude, outcomes in COVID-19 patients appear to be driven by obesity as well as active smoking, with no difference in mortality between cancer and noncancer patients.