Details

Autor(en) / Beteiligte

• Redmond, Sarah N.
• Jones, Lucas D.
• Sadri, Navid
• Schmotzer, Christine
• Navas, Maria E.
• Zabarsky, Trina F.
• Bhullar, Davinder
• Donskey, Curtis J.

Titel

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in vaccinated and unvaccinated healthcare personnel in a Veterans’ Affairs healthcare system

Ist Teil von

• Infection control and hospital epidemiology, 2022-09, Vol.43 (9), p.1300-1301

Ort / Verlag

New York, USA: Cambridge University Press

Erscheinungsjahr

2022

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• To the Editor—Coronavirus disease 2019 (COVID-19) mRNA vaccines substantially reduce but do not eliminate the risk for symptomatic and asymptomatic severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infections in healthcare personnel.1–5 In a recent report, 5 (12%) of 43 fully vaccinated personnel acquired mildly symptomatic or asymptomatic SARS-CoV-2 infection after higher-risk household exposures.6 Ongoing surveillance studies are needed to determine whethe such postvaccination “breakthrough” infections are caused by variants of concern with reduced in vitro susceptibility to neutralization by vaccine-induced antibodies.7 Surveillance studies can also provide comparative data on COVID-19 in unvaccinated personnel. Personnel health and infection control databases were reviewed to obtain information on exposure history, symptoms, and suspected transmission clusters based on contact tracing investigations. In a long-term care facility in Kentucky, an unvaccinated employee was implicated as the source of an outbreak that resulted in infections in 20 healthcare personnel and 26 residents with 3 resident deaths.1 There are also potential adverse effects for individuals who do not develop COVID-19.