The New England journal of medicine, 2021-04, Vol.384 (15), p.1424-1436
- Hughes, Christopher G
- Mailloux, Patrick T
- Devlin, John W
- Swan, Joshua T
- Sanders, Robert D
- Anzueto, Antonio
- Jackson, James C
- Hoskins, Aimee S
- Pun, Brenda T
- Orun, Onur M
- Raman, Rameela
- Stollings, Joanna L
- Kiehl, Amy L
- Duprey, Matthew S
- Bui, Lan N
- O’Neal, Hollis R
- Snyder, Allison
- Gropper, Michael A
- Guntupalli, Kalpalatha K
- Stashenko, Gregg J
- Patel, Mayur B
- Brummel, Nathan E
- Girard, Timothy D
- Dittus, Robert S
- Bernard, Gordon R
- Ely, E. Wesley
- Pandharipande, Pratik P
2021
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- Autor(en) / Beteiligte
- Hughes, Christopher G
- Mailloux, Patrick T
- Devlin, John W
- Swan, Joshua T
- Sanders, Robert D
- Anzueto, Antonio
- Jackson, James C
- Hoskins, Aimee S
- Pun, Brenda T
- Orun, Onur M
- Raman, Rameela
- Stollings, Joanna L
- Kiehl, Amy L
- Duprey, Matthew S
- Bui, Lan N
- O’Neal, Hollis R
- Snyder, Allison
- Gropper, Michael A
- Guntupalli, Kalpalatha K
- Stashenko, Gregg J
- Patel, Mayur B
- Brummel, Nathan E
- Girard, Timothy D
- Dittus, Robert S
- Bernard, Gordon R
- Ely, E. Wesley
- Pandharipande, Pratik P
- Titel
- Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis
- Ist Teil von
- The New England journal of medicine, 2021-04, Vol.384 (15), p.1424-1436
- Ort / Verlag
- United States: Massachusetts Medical Society
- Erscheinungsjahr
- 2021
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- The agent that should be used for light sedation of patients requiring mechanical ventilation is unclear. This randomized trial compared dexmedetomidine with propofol for the light sedation of critically ill patients with sepsis who required mechanical ventilation. No clinically important differences were found.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0028-4793eISSN: 1533-4406DOI: 10.1056/NEJMoa2024922Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8162695
- Format
- –
- Schlagworte
- Activities of daily living, Adult, Anesthesia, Body weight, Brain research, Cardiac arrhythmia, Cognition & reasoning, Cognition - drug effects, Cognitive ability, Coma, Conscious Sedation - methods, Critical care, Critical Illness, Delirium, Design, Dexmedetomidine - administration & dosage, Double-Blind Method, Drug dosages, FDA approval, Humans, Hypnotics and Sedatives - administration & dosage, Hypnotics and Sedatives - adverse effects, Inflammation, Intervention, Kaplan-Meier Estimate, Mechanical ventilation, Mortality, Nurses, Pain, Patients, Propofol, Propofol - administration & dosage, Quality of life, Respiration, Artificial, Sedatives, Sepsis, Sepsis - mortality, Sepsis - therapy, Statistical analysis, Ventilators