Details

Autor(en) / Beteiligte

• Smith, Adam R.
• Mill, Jonathan
• Lunnon, Katie

Titel

The molecular etiology of Alzheimer’s disease

Ist Teil von

• Brain pathology (Zurich, Switzerland), 2020-09, Vol.30 (5), p.964-965

Ort / Verlag

Indianapolis: John Wiley & Sons, Inc

Erscheinungsjahr

2020

Quelle

Wiley Online Library

Beschreibungen/Notizen

• Alzheimer’s disease (AD) is a growing global healthcare epidemic. Owing to advances in technology, genome‐scale studies of various layers of molecular information have been undertaken in recent years and robust variation in key loci have now been published and reproduced by others. This mini‐symposium highlights four key areas of current research in the field of molecular biology in AD, including articles focused on large‐scale genomic profiling, epigenetic research, integrative multi‐omic approaches and how these can be appropriately modeled to address reverse causality. This mini‐symposium provides a timely update on research focused on elucidating the molecular etiology of AD to date and highlights new methodological advances that could enable neuroscientists to identify novel therapeutic targets.