Details

Autor(en) / Beteiligte

• Condeni, Melanie Smith
• Basting, Alyson T.
• Costello, Patrick G.
• DePriest, Ashley
• Eriksson, Evert A.
• Evans, Heather
• Hertel, Kristie
• Holder, Andre L.
• Kester, Alyssa N.
• Kowalski, Kinsey R.
• Bell, Carolyn Magee
• McLean, Barbara
• Reichert, Michael
• Santibañez, Melissa
• Wieruszewski, Patrick M.
• Newsome, Andrea Sikora

Titel

Major publications in the critical care pharmacotherapy literature: 2019

Ist Teil von

• Journal of critical care, 2021-04, Vol.62, p.197-205

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2021

Quelle

ScienceDirect

Beschreibungen/Notizen

• To summarize selected meta-analyses and trials related to critical care pharmacotherapy published in 2019. The Critical Care Pharmacotherapy Literature Update (CCPLU) Group screened 36 journals monthly for impactful articles and reviewed 113 articles during 2019 according to Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) criteria. Articles with a 1A grade, including three clinical practice guidelines, six meta-analyses, and five original research trials are reviewed here from those included in the monthly CCPLU. Clinical practice guidelines on the use of polymyxins and antiarrhythmic drugs in cardiac arrest as well as meta-analyses on antipsychotic use in delirium, stress ulcer prophylaxis (SUP), and vasoactive medications in septic shock and cardiac arrest were summarized. Original research trials evaluated delirium, sedation, neuromuscular blockade, SUP, anticoagulation reversal, and hemostasis. This clinical review and expert opinion provides summary and perspectives of clinical practice impact on influential critical care pharmacotherapy publications in 2019. •2019 articles of interest in critical care pharmacology are included here.•Included are 3 clinical practice guidelines, 6 meta-analyses, and 5 original trials•Topics include drug use in cardiac arrest, septic shock, delirium, sedation, stress ulcer prophylaxis, and anticoagulation reversal