Details

Autor(en) / Beteiligte

• Waihrich, E
• Clavel, P
• Mendes, G A C
• Iosif, C
• Moraes Kessler, I
• Mounayer, C

Titel

Influence of Carotid Siphon Anatomy on Brain Aneurysm Presentation

Ist Teil von

• American journal of neuroradiology : AJNR, 2017-09, Vol.38 (9), p.1771-1775

Ort / Verlag

United States: American Society of Neuroradiology

Erscheinungsjahr

2017

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Intracranial aneurysm is a devastating disease of complex etiology that is not fully understood. The purpose of this study was to assess the implications of carotid siphon anatomy for the formation and development of intracranial aneurysms. Between January 2007 and May 2015, lateral view digital subtraction angiographic images of 692 consecutive patients with intracranial aneurysms treated in our department of interventional neuroradiology were reviewed and had their angles measured. Data on the location, presentation, and size of the lesions were collected and evaluated by multivariate analysis in relation to the measured angles. Of 692 aneurysms, 225 (32.51%) ruptured and 467 (67.49%) unruptured, 218 (31.50%) were in the carotid siphon and 474 (68.50%) were distal to the siphon, and the mean aneurysm size was 7.99 ± 6.95 mm. Multivariate analysis showed an association between angles of >15.40° and rupture ( = .005), postsiphon location ( = .034), and aneurysm size of >1.001 mm ( = .015). Multivariate analysis also showed that every 1-year increase in patient age produced an increase of 1.002 mm in aneurysm size ( = .015). There was a significant independent direct relation of greater anterior knee angle with intracranial aneurysms located distal to the carotid siphon, larger aneurysms, and greater risk of rupture. These findings may be associated with the hemodynamic interactions of blood flow and the curvature of the carotid siphon.