Medical hypotheses, 2021-03, Vol.148, p.110508-110508, Article 110508
2021
Details
- Autor(en) / Beteiligte
- Titel
- Antihistamine and cationic amphiphilic drugs, old molecules as new tools against the COVID-19?
- Ist Teil von
- Medical hypotheses, 2021-03, Vol.148, p.110508-110508, Article 110508
- Ort / Verlag
- United States: Elsevier Ltd
- Erscheinungsjahr
- 2021
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Several studies have reported that certain psychoactive drugs could have a protective effect against SARS-CoV-2. Herein, we propose that antihistamines (anti-H1) and cationic amphiphilic drugs (CAD), specifically, have the capacity to disrupt virus entry and replication. In addition, several of these molecules have limited side effects and as such could be promising prophylactic candidates against SARS-CoV-2 infection.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0306-9877eISSN: 1532-2777DOI: 10.1016/j.mehy.2021.110508Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7830196
- Format
- –
- Schlagworte
- COVID-19 - virology, COVID-19 Drug Treatment, Drug Repositioning, Histamine H1 Antagonists - pharmacology, Humans, Life Sciences, Models, Biological, Pandemics, Pharmaceutical sciences, SARS-CoV-2 - drug effects, SARS-CoV-2 - physiology, Surface-Active Agents - pharmacology, Virus Internalization - drug effects, Virus Replication - drug effects