Details

Autor(en) / Beteiligte

• Wadhwa, Ashutosh
• Fisher, Kiva A
• Silver, Rachel
• Koh, Mitsuki
• Arons, Melissa M
• Miller, David A
• McIntyre, Anne F
• Vuong, Jeni T
• Kim, Kaylee
• Takamiya, Mayuko
• Binder, Alison M
• Tate, Jacqueline E
• Armstrong, Paige A
• Black, Stephanie R
• Mennella, Connie C
• Levin, Rebecca
• Gubser, Jane
• Jones, Bridgette
• Welbel, Sharon F
• Moonan, Patrick K
• Curran, Kathryn
• Ghinai, Isaac
• Doshi, Reena
• Zawitz, Chad J

Titel

Identification of Presymptomatic and Asymptomatic Cases Using Cohort-Based Testing Approaches at a Large Correctional Facility—Chicago, Illinois, USA, May 2020

Ist Teil von

• Clinical infectious diseases, 2021-03, Vol.72 (5), p.e128-e135

Ort / Verlag

US: Oxford University Press

Erscheinungsjahr

2021

Quelle

Oxford Journals 2020 Medicine

Beschreibungen/Notizen

• Abstract Background Coronavirus disease 2019 (COVID-19) continues to cause significant morbidity and mortality worldwide. Correctional and detention facilities are at high risk of experiencing outbreaks. We aimed to evaluate cohort-based testing among detained persons exposed to laboratory-confirmed cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in order to identify presymptomatic and asymptomatic cases. Methods During 1–19 May 2020, 2 testing strategies were implemented in 12 tiers or housing units of the Cook County Jail, Chicago, Illinois. Detained persons were approached to participate in serial testing (n = 137) and offered tests at 3 time points over 14 days (day 1, days 3–5, and days 13–14). The second group was offered a single test and interview at the end of a 14-day quarantine period (day 14 group) (n = 87). Results 224 detained persons were approached for participation and, of these, 194 (87%) participated in ≥1 interview and 172 (77%) had ≥1 test. Of the 172 tested, 19 were positive for SARS-CoV-2. In the serial testing group, 17 (89%) new cases were detected, 16 (84%) on day 1, 1 (5%) on days 3–5, and none on days 13–14; in the day 14 group, 2 (11%) cases were identified. More than half (12/19; 63%) of the newly identified cases were presymptomatic or asymptomatic. Conclusions Our findings highlight the utility of cohort-based testing promptly after initiating quarantine within a housing tier. Cohort-based testing efforts identified new SARS-CoV-2 asymptomatic and presymptomatic infections that may have been missed by symptom screening alone. Our findings suggest that early cohort-based testing in detained persons helped identify new SARS-CoV-2 asymptomatic and presymptomatic infections that may have been missed by symptom screening alone. Frequency of testing may be dependent on status of outbreak in the facility.