Biochemical Society transactions, 2020-12, Vol.48 (6), p.2457-2466
2020
Details
- Autor(en) / Beteiligte
- Titel
- Developments in tandem ion mobility mass spectrometry
- Ist Teil von
- Biochemical Society transactions, 2020-12, Vol.48 (6), p.2457-2466
- Ort / Verlag
- England: Portland Press Ltd
- Erscheinungsjahr
- 2020
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Ion Mobility (IM) coupled to mass spectrometry (MS) is a useful tool for separating species of interest out of small quantities of heterogenous mixtures via a combination of m/z and molecular shape. While tandem MS instruments are common, instruments which employ tandem IM are less so with the first commercial IM-MS instrument capable of multiple IM selection rounds being released in 2019. Here we explore the history of tandem IM instruments, recent developments, the applications to biological systems and expected future directions.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0300-5127eISSN: 1470-8752DOI: 10.1042/BST20190788Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7752082
- Format
- –
- Schlagworte
- Biophysics, Biophysics - history, Biophysics - trends, Chemistry Techniques, Analytical - history, Chemistry Techniques, Analytical - trends, Equipment Design, History, 20th Century, History, 21st Century, Ion Mobility Spectrometry - instrumentation, Ion Mobility Spectrometry - methods, Ion Mobility Spectrometry - trends, Ions, Review, Structural Biology, Tandem Mass Spectrometry - instrumentation, Tandem Mass Spectrometry - methods, Tandem Mass Spectrometry - trends