Details

Autor(en) / Beteiligte

• Ray-Offor, Emeka
• Opusunju, Kalanne Ada

Titel

Current status of peptic ulcer disease in Port Harcourt metropolis, Nigeria

Ist Teil von

• African health sciences, 2020-09, Vol.20 (3), p.1446-1451

Ort / Verlag

Uganda: Makerere Medical School

Erscheinungsjahr

2020

Quelle

MEDLINE

Beschreibungen/Notizen

• Epidemiological studies on peptic ulcer disease (PUD) have shown a recent decrease in hospital admissions in Western countries. This paper aimed to study the current status and risk factors of PUD in a Nigerian metropolis. A cross-sectional study of symptomatic patients at upper gastrointestinal (GI) endoscopy diagnosed with PUD from February 2014 to September 2019 at a referral endoscopy facility in Port Harcourt, Niger delta region of Nigeria. The variables studied included demographics, symptoms and duration, blood group, chronic non-steroidal anti-inflammatory (NSAID) use, smoking, endoscopic and histology findings. Statistical analysis was performed using SPSS version 20. A total of 434 upper GI endoscopies were performed during the study period with thirty-one diagnosis of PUD made. The mean age of gastric ulcer (GU) and duodenal ulcer (DU) cases were 54.4 ± 20.2yrs and 48.1 ± 14.5yrs respectively (p = 0.367). GU to DU ratio was 1.4:1. infection, chronic NSAID use and blood group O were seen in 7(22.5%), 8(25.8%) and 18(72.0%) respectively. Major indication in 21(67.7%) cases was gastrointestinal bleeding. There is a low diagnostic rate of PUD (6.7%) with pre-pyloric antral gastric ulcers as most common type and multifactorial aetiology.