Details

Autor(en) / Beteiligte

• Mohr, Nicholas M.
• Harland, Karisa K.
• Krishnadasan, Anusha
• Eyck, Patrick Ten
• Mower, William R.
• Willey, James
• Chisolm-Straker, Makini
• Lim, Stephen C.
• McDonald, L. Clifford
• Kutty, Preeta K.
• Hesse, Elisabeth
• Santibanez, Scott
• Talan, David A.
• Bahamon, Monica
• Carlson, Jestin N.
• Driver, Brian
• Faine, Brett
• Galbraith, James
• Giordano, Philip A.
• Haran, John P.
• Higgins, Amanda
• Hinson, Jeremiah
• House, Stacey
• Idris, Ahamed H.
• Kean, Efrat
• Krebs, Elizabeth
• Kurz, Michael C.
• Lee, Lilly
• Liang, Stephen Y.
• Montoy, Juan Carlos C.
• Moran, Gregory
• Nandi, Utsav
• Pathmarajah, Kavitha
• Paxton, James H.
• Perez, Yesenia
• Richardson, Lynne D.
• Rodriguez, Robert M.
• Rothman, Richard
• Schrading, Walter A.
• Shuck, Jessica
• Slev, Patricia
• Smithline, Howard A.
• Souffront, Kimberly
• Steele, Mark
• Stubbs, Amy
• Swanson, Morgan
• Tiao, Josh
• Torres, Jesus R.
• Trent, Stacy
• Uribe, Lisandra
• Venkat, Arvind
• Volturo, Gregory
• Wallace, Kelli
• Weber, Kurt D.

Titel

Diagnosed and Undiagnosed COVID-19 in US Emergency Department Health Care Personnel: A Cross-sectional Analysis

Ist Teil von

• Annals of emergency medicine, 2021-07, Vol.78 (1), p.27-34

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2021

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• We determine the percentage of diagnosed and undiagnosed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among a sample of US emergency department (ED) health care personnel before July 2020. This was a cross-sectional analysis of ED health care personnel in 20 geographically diverse university-affiliated EDs from May 13, to July 8, 2020, including case counts of prior laboratory-confirmed coronavirus disease 2019 (COVID-19) diagnoses among all ED health care personnel, and then point-in-time serology (with confirmatory testing) and reverse transcriptase–polymerase chain reaction testing in a sample of volunteers without a previous COVID-19 diagnosis. Health care staff were categorized as clinical (physicians, advanced practice providers, and nurses) and nonclinical (clerks, social workers, and case managers). Previously undiagnosed infection was based on positive SARS-CoV-2 serology or reverse transcriptase–polymerase chain reaction result among health care personnel without prior diagnosis. Diagnosed COVID-19 occurred in 2.8% of health care personnel (193/6,788), and the prevalence was similar for nonclinical and clinical staff (3.8% versus 2.7%; odds ratio 1.5; 95% confidence interval 0.7 to 3.2). Among 1,606 health care personnel without previously diagnosed COVID-19, 29 (1.8%) had evidence of current or past SARS-CoV-2 infection. Most (62%; 18/29) who were seropositive did not think they had been infected, 76% (19/25) recalled COVID-19–compatible symptoms, and 89% (17/19) continued to work while symptomatic. Accounting for both diagnosed and undiagnosed infections, 4.6% (95% confidence interval 2.8% to 7.5%) of ED health care personnel were estimated to have been infected with SARS-CoV-2, with 38% of those infections undiagnosed. In late spring and early summer 2020, the estimated prevalence of severe acute respiratory syndrome coronavirus 2 infection was 4.6%, and greater than one third of infections were undiagnosed. Undiagnosed SARS-CoV-2 infection may pose substantial risk for transmission to other staff and patients.