The New England journal of medicine, 2020-12, Vol.383 (27), p.2603-2615
- Polack, Fernando P
- Thomas, Stephen J
- Kitchin, Nicholas
- Absalon, Judith
- Gurtman, Alejandra
- Lockhart, Stephen
- Perez, John L
- Pérez Marc, Gonzalo
- Moreira, Edson D
- Zerbini, Cristiano
- Bailey, Ruth
- Swanson, Kena A
- Roychoudhury, Satrajit
- Koury, Kenneth
- Li, Ping
- Kalina, Warren V
- Cooper, David
- Frenck, Robert W
- Hammitt, Laura L
- Türeci, Özlem
- Nell, Haylene
- Schaefer, Axel
- Ünal, Serhat
- Tresnan, Dina B
- Mather, Susan
- Dormitzer, Philip R
- Şahin, Uğur
- Jansen, Kathrin U
- Gruber, William C
2020
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- Autor(en) / Beteiligte
- Polack, Fernando P
- Thomas, Stephen J
- Kitchin, Nicholas
- Absalon, Judith
- Gurtman, Alejandra
- Lockhart, Stephen
- Perez, John L
- Pérez Marc, Gonzalo
- Moreira, Edson D
- Zerbini, Cristiano
- Bailey, Ruth
- Swanson, Kena A
- Roychoudhury, Satrajit
- Koury, Kenneth
- Li, Ping
- Kalina, Warren V
- Cooper, David
- Frenck, Robert W
- Hammitt, Laura L
- Türeci, Özlem
- Nell, Haylene
- Schaefer, Axel
- Ünal, Serhat
- Tresnan, Dina B
- Mather, Susan
- Dormitzer, Philip R
- Şahin, Uğur
- Jansen, Kathrin U
- Gruber, William C
- Titel
- Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
- Ist Teil von
- The New England journal of medicine, 2020-12, Vol.383 (27), p.2603-2615
- Ort / Verlag
- United States: Massachusetts Medical Society
- Erscheinungsjahr
- 2020
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- A vaccine containing an RNA molecule encoding the SARS-CoV-2 spike protein was tested in a trial in which two injections were given 3 weeks apart. After the second injection, Covid-19 developed in 162 patients receiving placebo, with a median follow-up of 2 months, and in 8 patients receiving the vaccine. Side effects were mainly mild-to-moderate injection-site pain and swelling.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0028-4793eISSN: 1533-4406DOI: 10.1056/NEJMoa2034577Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7745181
- Format
- –
- Schlagworte
- Adolescent, Adult, Age, Aged, BNT162 Vaccine, Confidence intervals, Coronaviridae, Coronaviruses, COVID-19, COVID-19 - immunology, COVID-19 - prevention & control, COVID-19 vaccines, COVID-19 Vaccines - administration & dosage, COVID-19 Vaccines - adverse effects, COVID-19 Vaccines - immunology, Fatigue - etiology, Female, Headache - etiology, Hepatitis, HIV, Human immunodeficiency virus, Humans, Illnesses, Immunization, Secondary, Infections, Male, Middle Aged, mRNA, mRNA Vaccines, Nanoparticles, Older people, Original, Pandemics, Population, Safety, SARS-CoV-2 - genetics, Severe acute respiratory syndrome coronavirus 2, Single-Blind Method, Spike protein, Treatment Outcome, Vaccine efficacy, Vaccines, Vaccines, Synthetic, Young Adult