The New England journal of medicine, 2020-12, Vol.383 (24), p.2389-2390
2020
Details
- Autor(en) / Beteiligte
- Titel
- Covid-19–Associated Myopathy Caused by Type I Interferonopathy
- Ist Teil von
- The New England journal of medicine, 2020-12, Vol.383 (24), p.2389-2390
- Ort / Verlag
- United States: Massachusetts Medical Society
- Erscheinungsjahr
- 2020
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Generalized, predominantly proximal weakness and a greatly elevated creatine kinase level developed in a man with Covid-19. Immunohistochemical analysis of a muscle-biopsy specimen revealed abnormal expression of MHC-1 and myxovirus resistance protein A on muscle fibers, suggesting type I interferonopathy.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0028-4793eISSN: 1533-4406DOI: 10.1056/NEJMc2031085Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7722689
- Format
- –
- Schlagworte
- Adenosine Monophosphate - analogs & derivatives, Adenosine Monophosphate - therapeutic use, Adult, Alanine - analogs & derivatives, Alanine - therapeutic use, Biopsy, Coronaviruses, Correspondence, COVID-19, COVID-19 - complications, Creatine, Creatine kinase, Humans, Infections, Interferon Type I - metabolism, Major histocompatibility complex, Male, Methylprednisolone - therapeutic use, Muscle, Skeletal - pathology, Muscular Diseases - virology, Myopathy, Myxovirus Resistance Proteins - metabolism, Prednisone - therapeutic use, Proteins, Severe acute respiratory syndrome coronavirus 2, Viral infections