Details

Autor(en) / Beteiligte

• La Buissonnière-Ariza, Valérie
• Séguin, Jean R.
• Nassim, Marouane
• Boivin, Michel
• Pine, Daniel S.
• Lepore, Franco
• Tremblay, Richard E.
• Maheu, Françoise S.

Titel

Chronic harsh parenting and anxiety associations with fear circuitry function in healthy adolescents: A preliminary study

Ist Teil von

• Biological psychology, 2019-07, Vol.145, p.198-210

Ort / Verlag

Netherlands: Elsevier B.V

Erscheinungsjahr

2019

Quelle

MEDLINE

Beschreibungen/Notizen

• •Harsh parenting was associated with decreased amygdala deactivations to CS+ vs CS- and amygdala-insula connectivity.•Distinct patterns of anxiety differences emerged in amygdala- rACC connectivity according to harsh parenting levels.•Distinct anxiety differences also emerged in terms of subjective fear ratings according to harsh parenting levels. Previous studies have reported altered fear circuitry function during fear conditioning in highly anxious individuals and in adults with a history of severe childhood adversity; less is known regarding younger populations and more common forms of adversity. We investigated fear circuitry functioning in healthy youths with histories of high (HH) or low (LH) chronic harsh parenting and high (HA) or low (LA) anxiety levels. 84 youths aged 13–16 performed an fMRI fear conditioning task. HH displayed decreased selective medial temporal lobe deactivations to CS+> CS− relative to LH. In addition, we found less amygdala-insula connectivity in HH vs LH. Interestingly, we observed distinct patterns of anxiety differences in amygdala-rostral ACC connectivity and subjective fear ratings depending on harsh parenting levels, suggesting a history of harsh parenting is linked with unique neural and behavioral anxious manifestations, which are different from anxiety manifestations in a context of low adversity.