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Cutaneous examination revealed multiple discrete, mildly tender, pink-red coloured, shiny, dome-shaped, umbilicated papules (ranging from 3–8 mm in diameter) with a surrounding intense erythematous halo distributed over the trunk and proximal upper extremities; some lesions had focal erosions and crusting (figure 1). Multiple pink-red dome-shaped umbilicated papules with surrounding erythematous flare, focal erosion, and crusting overlying the trunk and proximal upper limb; (inset) magnified view of inflammed molluscum contagiosum demonstrating the typical beginning of the end sign. Spontaneous regression of highly immunogenic Molluscum contagiosum virus (MCV)-induced skin lesions is associated with plasmacytoid dendritic cells and IFN-DC infiltration.