Details

Autor(en) / Beteiligte

• McEvoy, James P
• Martin, Philip
• Khaleel, Arshad
• Dissanayeke, Shobana

Titel

Titanium Kirschner Wires Resist Biofilms Better Than Stainless Steel and Hydroxyapatite-coated Wires: An In Vitro Study

Ist Teil von

• Strategies in trauma and limb reconstruction, 2019-05, Vol.14 (2), p.57-64

Ort / Verlag

India: Jaypee Brothers Medical Publishers

Erscheinungsjahr

2019

Link zum Volltext

Quelle

EZB Free E-Journals

Beschreibungen/Notizen

• External fixation surgery is frequently complicated by percutaneous pin site infection focused on the surface of the fixator pin. The primary aim of this study was to compare biofilm growth of clinically isolated pin site bacteria on Kirschner wires of different materials. Two commonly infecting species, and , were isolated from patients' pin sites. A stirred batch bioreactor was used to grow these bacteria as single culture and co-cultured biofilms on Kirschner wires made of three different materials: stainless steel, hydroxyapatite-coated steel and titanium alloy. We found that the surface density of viable cells within these biofilms was 3x higher on stainless steel and 4.5x higher on hydroxyapatite-coated wires than on the titanium wires. Our results suggest that the lower rates of clinical pin site infection seen with titanium Kirschner wires are due to, at least in part, titanium's better bacterial biofilm resistance. Our results are consistent with clinical studies which have found that pin site infection rates are reduced by the use of titanium relative to stainless steel or hydroxyapatite-coated pins. McEvoy JP, Martin P, Khaleel A, Titanium Kirschner Wires Resist Biofilms Better Than Stainless Steel and Hydroxyapatite-coated Wires: An Study. Strategies Trauma Limb Reconstr 2019;14(2):57-64.