Details

Autor(en) / Beteiligte

• Muenchhoff, Maximilian
• Mairhofer, Helga
• Nitschko, Hans
• Grzimek-Koschewa, Natascha
• Hoffmann, Dieter
• Berger, Annemarie
• Rabenau, Holger
• Widera, Marek
• Ackermann, Nikolaus
• Konrad, Regina
• Zange, Sabine
• Graf, Alexander
• Krebs, Stefan
• Blum, Helmut
• Sing, Andreas
• Liebl, Bernhard
• Wölfel, Roman
• Ciesek, Sandra
• Drosten, Christian
• Protzer, Ulrike
• Boehm, Stephan
• Keppler, Oliver T

Titel

Multicentre comparison of quantitative PCR-based assays to detect SARS-CoV-2, Germany, March 2020

Ist Teil von

• Euro surveillance : bulletin européen sur les maladies transmissibles, 2020-06, Vol.25 (24), p.1

Ort / Verlag

Sweden: Centre Europeen pour la Surveillance Epidemiologique du SIDA (European Centre for the Epidemiological Monitoring of AIDS)

Erscheinungsjahr

2020

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Containment strategies and clinical management of coronavirus disease (COVID-19) patients during the current pandemic depend on reliable diagnostic PCR assays for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we compare 11 different RT-PCR test systems used in seven diagnostic laboratories in Germany in March 2020. While most assays performed well, we identified detection problems in a commonly used assay that may have resulted in false-negative test results during the first weeks of the pandemic.