Leukemia, 2020-04, Vol.34 (4), p.1197-1201
2020
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Details
- Autor(en) / Beteiligte
- Titel
- Iberdomide (CC-220) is a potent cereblon E3 ligase modulator with antitumor and immunostimulatory activities in lenalidomide- and pomalidomide-resistant multiple myeloma cells with dysregulated CRBN
- Ist Teil von
- Leukemia, 2020-04, Vol.34 (4), p.1197-1201
- Ort / Verlag
- London: Nature Publishing Group UK
- Erscheinungsjahr
- 2020
- Quelle
- MEDLINE
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0887-6924eISSN: 1476-5551DOI: 10.1038/s41375-019-0620-8Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7214241
- Format
- –
- Schlagworte
- 13, 13/1, 13/106, 13/2, 13/31, 13/51, 38, 38/23, 631/67/1059/2326, 692/699/1541/1990/804, Adaptor Proteins, Signal Transducing - antagonists & inhibitors, Adaptor Proteins, Signal Transducing - genetics, Adaptor Proteins, Signal Transducing - immunology, Adaptor Proteins, Signal Transducing - metabolism, Anticancer properties, Antineoplastic Combined Chemotherapy Protocols - pharmacology, Cancer Research, Care and treatment, Cellular proteins, Clinical Trials as Topic, Critical Care Medicine, Development and progression, Drug Resistance, Neoplasm - drug effects, Genetic aspects, Genetic regulation, Health aspects, Hematology, Heterocyclic Compounds, 4 or More Rings - administration & dosage, Humans, Immunity, Immunostimulation, Immunotherapy, Intensive, Internal Medicine, Lenalidomide - administration & dosage, Letter, Leukocytes, Mononuclear - drug effects, Leukocytes, Mononuclear - pathology, Medicine, Medicine & Public Health, Multiple myeloma, Multiple Myeloma - drug therapy, Multiple Myeloma - immunology, Multiple Myeloma - metabolism, Multiple Myeloma - pathology, Oncology, Targeted cancer therapy, Thalidomide - administration & dosage, Thalidomide - analogs & derivatives, Tumor Cells, Cultured, Ubiquitin-protein ligase, Ubiquitin-Protein Ligases