Details

Autor(en) / Beteiligte

• Xu, Min
• Qin, Xuan
• Astion, Michael L
• Rutledge, Joe C
• Simpson, Joanne
• Jerome, Keith R
• Englund, Janet A
• Zerr, Danielle M
• Migita, Russell T
• Rich, Shannon
• Childs, John C
• Cent, Anne
• Del Beccaro, Mark A

Titel

Implementation of filmarray respiratory viral panel in a core laboratory improves testing turnaround time and patient care

Ist Teil von

• American journal of clinical pathology, 2013-01, Vol.139 (1), p.118-123

Ort / Verlag

England: Oxford University Press

Erscheinungsjahr

2013

Link zum Volltext

Quelle

Oxford Journals 2020 Medicine

Beschreibungen/Notizen

• The FilmArray respiratory virus panel detects 15 viral agents in respiratory specimens using polymerase chain reaction. We performed FilmArray respiratory viral testing in a core laboratory at a regional children's hospital that provides service 24 hours a day 7 days a week. The average and median turnaround time were 1.6 and 1.4 hours, respectively, in contrast to 7 and 6.5 hours documented 1 year previously at an on-site reference laboratory using a direct fluorescence assay (DFA) that detected 8 viral agents. During the study period, rhinovirus was detected in 20% and coronavirus in 6% of samples using FilmArray; these viruses would not have been detected with DFA. We followed 97 patients with influenza A or influenza B who received care at the emergency department (ED). Overall, 79 patients (81%) were given oseltamivir in a timely manner defined as receiving the drug in the ED, a prescription in the ED, or a prescription within 3 hours of ED discharge. Our results demonstrate that molecular technology can be successfully deployed in a nonspecialty, high-volume, multidisciplinary core laboratory.