Details

Autor(en) / Beteiligte

• Regensburger, Adrian P.
• Wagner, Alexandra L.
• Claussen, Jing
• Waldner, Maximilian J.
• Knieling, Ferdinand

Titel

Shedding light on pediatric diseases: multispectral optoacoustic tomography at the doorway to clinical applications

Ist Teil von

• Molecular and cellular pediatrics, 2020-03, Vol.7 (1), p.3-3, Article 3

Ort / Verlag

Berlin/Heidelberg: Springer Berlin Heidelberg

Erscheinungsjahr

2020

Link zum Volltext

Quelle

SpringerLink (Online service)

Beschreibungen/Notizen

• Optoacoustic imaging (OAI), or photoacoustic imaging (PAI), has fundamentally influenced basic science by providing high-resolution visualization of biological mechanisms. With the introduction of multispectral optoacoustic tomography (MSOT), these technologies have now moved closer to clinical applications. MSOT utilizes short-pulsed near-infrared laser light to induce thermoelastic expansion in targeted tissues. This results in acoustic pressure waves, which are used to resolve specific endo- and exogenous chromophores. Especially in the pediatric population, this non-invasive imaging approach might hold fundamental advantages compared to conventional cross-sectional imaging modalities. As this technology allows the visualization of quantitative molecular tissue composition at high spatial resolution non-invasively in sufficient penetration depth, it paves the way to personalized medicine in pediatric diseases.