Angewandte Chemie (International ed.), 2020-01, Vol.59 (5), p.1776-1785
International ed. in English, 2020
Details
- Autor(en) / Beteiligte
- Titel
- Surface Plasmon Resonance Microscopy: From Single‐Molecule Sensing to Single‐Cell Imaging
- Ist Teil von
- Angewandte Chemie (International ed.), 2020-01, Vol.59 (5), p.1776-1785
- Auflage
- International ed. in English
- Ort / Verlag
- Germany: Wiley Subscription Services, Inc
- Erscheinungsjahr
- 2020
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Surface plasmon resonance microscopy (SPRM) is a versatile platform for chemical and biological sensing and imaging. Great progress in exploring its applications, ranging from single‐molecule sensing to single‐cell imaging, has been made. In this Minireview, we introduce the principles and instrumentation of SPRM. We also summarize the broad and exciting applications of SPRM to the analysis of single entities. Finally, we discuss the challenges and limitations associated with SPRM and potential solutions. Surface plasmon resonance microscopy has emerged as a versatile platform for single‐molecule sensing and single‐cell imaging with high spatiotemporal resolution. This Minireview highlights the recent advances in the SPRM‐based analysis of single entities. Future challenges and their limitations as well as potential research directions are discussed.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1433-7851eISSN: 1521-3773DOI: 10.1002/anie.201908806Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7020607
- Format
- –
- Schlagworte
- binding kinetics, Biosensing Techniques - methods, Cell surface, Detection, Humans, Imaging, Instrumentation, label-free methods, Microscopy, Microscopy - methods, Organic chemistry, Resonance, sensors, Single-Cell Analysis - methods, single-cell imaging, Surface plasmon resonance, Surface Plasmon Resonance - methods