Details

Autor(en) / Beteiligte

• Krämer, Friederike
• Hüsken, Ricarda
• Krüdewagen, Eva Maria
• Deuster, Katrin
• Blagburn, Byron
• Straubinger, Reinhard K.
• Butler, Jamie
• Fingerle, Volker
• Charles, Sam
• Settje, Terry
• Schunack, Bettina
• Stanneck, Dorothee

Titel

Prevention of transmission of Borrelia burgdorferi sensu lato and Anaplasma phagocytophilum by Ixodes spp. ticks to dogs treated with the Seresto® collar (imidacloprid 10% + flumethrin 4.5%)

Ist Teil von

• Parasitology research (1987), 2020-01, Vol.119 (1), p.299-315

Ort / Verlag

Berlin/Heidelberg: Springer Berlin Heidelberg

Erscheinungsjahr

2020

Quelle

MEDLINE

Beschreibungen/Notizen

• The capability of imidacloprid 10% + flumethrin 4.5% (Seresto®) collars to prevent transmission of Borrelia burgdorferi sensu lato ( Bb sl) and Anaplasma phagocytophilum ( Ap ) by naturally infected ticks was evaluated in two studies with 44 dogs. In each study, one group served as non-treated control, whereas the other groups were treated with the Seresto® collar. All dogs were exposed to naturally Bb sl- and Ap -infected hard ticks ( Ixodes ricinus , Ixodes scapularis ). In study 1, tick infestation was performed on study day (SD) 63 (2 months post-treatment [p.t.]); in study 2, it was performed on SD 32 (one month p.t.) respectively SD 219 (seven months p.t.). In situ tick counts were performed 2 days after infestation. Tick counts and removals followed 6 (study 1) or 5 days (study 2) later. Blood sampling was performed for the detection of specific Bb sl and Ap antibodies and, in study 1, for the documentation of Ap DNA by PCR. Skin biopsies were examined for Bb sl by PCR and culture (only study 1). The efficacy against Ixodes spp. was 100% at all time points. In study 1, two of six non-treated dogs became infected with Bb sl, and four of six tested positive for Ap ; none of the treated dogs tested positive for Bb sl or Ap . In study 2, ten of ten non-treated dogs became infected with Bb sl and Ap ; none of the treated dogs tested positive for Bb sl or Ap ; 100% acaricidal efficacy was shown in both studies. Transmission of Bb sl and Ap was successfully blocked for up to 7 months.