Details

Autor(en) / Beteiligte

• Shinde, Vasant
• Narasimhan, Vagheesh M.
• Rohland, Nadin
• Mallick, Swapan
• Mah, Matthew
• Lipson, Mark
• Nakatsuka, Nathan
• Adamski, Nicole
• Broomandkhoshbacht, Nasreen
• Ferry, Matthew
• Lawson, Ann Marie
• Michel, Megan
• Oppenheimer, Jonas
• Stewardson, Kristin
• Jadhav, Nilesh
• Kim, Yong Jun
• Chatterjee, Malavika
• Munshi, Avradeep
• Panyam, Amrithavalli
• Waghmare, Pranjali
• Yadav, Yogesh
• Patel, Himani
• Kaushik, Amit
• Thangaraj, Kumarasamy
• Meyer, Matthias
• Patterson, Nick
• Rai, Niraj
• Reich, David

Titel

An Ancient Harappan Genome Lacks Ancestry from Steppe Pastoralists or Iranian Farmers

Ist Teil von

• Cell, 2019-10, Vol.179 (3), p.729-735.e10

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2019

Quelle

MEDLINE

Beschreibungen/Notizen

• We report an ancient genome from the Indus Valley Civilization (IVC). The individual we sequenced fits as a mixture of people related to ancient Iranians (the largest component) and Southeast Asian hunter-gatherers, a unique profile that matches ancient DNA from 11 genetic outliers from sites in Iran and Turkmenistan in cultural communication with the IVC. These individuals had little if any Steppe pastoralist-derived ancestry, showing that it was not ubiquitous in northwest South Asia during the IVC as it is today. The Iranian-related ancestry in the IVC derives from a lineage leading to early Iranian farmers, herders, and hunter-gatherers before their ancestors separated, contradicting the hypothesis that the shared ancestry between early Iranians and South Asians reflects a large-scale spread of western Iranian farmers east. Instead, sampled ancient genomes from the Iranian plateau and IVC descend from different groups of hunter-gatherers who began farming without being connected by substantial movement of people. [Display omitted] •The individual was from a population that is the largest source of ancestry for South Asians•Iranian-related ancestry in South Asia split from Iranian plateau lineages >12,000 years ago•First farmers of the Fertile Crescent contributed little to no ancestry to later South Asians A genome from the Indus Valley Civilization is from a population that is the largest source for South Asians. The population has no detectable ancestry from Steppe pastoralists or from Anatolian and Iranian farmers, suggesting farming in South Asia arose from local foragers rather than from large-scale migration from the West.