Details

Autor(en) / Beteiligte

• Krishnaswami, Ashok
• Steinman, Michael A.
• Goyal, Parag
• Zullo, Andrew R.
• Anderson, Timothy S.
• Birtcher, Kim K.
• Goodlin, Sarah J.
• Maurer, Mathew S.
• Alexander, Karen P.
• Rich, Michael W.
• Tjia, Jennifer

Titel

Deprescribing in Older Adults With Cardiovascular Disease

Ist Teil von

• Journal of the American College of Cardiology, 2019-05, Vol.73 (20), p.2584-2595

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2019

Quelle

Access via ScienceDirect (Elsevier)

Beschreibungen/Notizen

• Deprescribing, an integral component of a continuum of good prescribing practices, is the process of medication withdrawal or dose reduction to correct or prevent medication-related complications, improve outcomes, and reduce costs. Deprescribing is particularly applicable to the commonly encountered multimorbid older adult with cardiovascular disease and concomitant geriatric conditions such as polypharmacy, frailty, and cognitive dysfunction—a combination rarely addressed in current clinical practice guidelines. Triggers to deprescribe include present or expected adverse drug reactions, unnecessary polypharmacy, and the need to align medications with goals of care when life expectancy is reduced. Using a framework to deprescribe, this review addresses the rationale, evidence, and strategies for deprescribing cardiovascular and some noncardiovascular medications. [Display omitted] •Multimorbid older adults with CVD are disproportionately affected by medication-related issues.•Deprescribing is an integral component of good prescribing practice.•Incorporating deprescribing into routine cardiovascular care can reduce treatment burden and morbidity in older adults.