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Ovarian cancer statistics, 2018
CA: a cancer journal for clinicians, 2018-07, Vol.68 (4), p.284-296
Torre, Lindsey A.
Trabert, Britton
DeSantis, Carol E.
Miller, Kimberly D.
Samimi, Goli
Runowicz, Carolyn D.
Gaudet, Mia M.
Jemal, Ahmedin
Siegel, Rebecca L.
2018
Details
Autor(en) / Beteiligte
Torre, Lindsey A.
Trabert, Britton
DeSantis, Carol E.
Miller, Kimberly D.
Samimi, Goli
Runowicz, Carolyn D.
Gaudet, Mia M.
Jemal, Ahmedin
Siegel, Rebecca L.
Titel
Ovarian cancer statistics, 2018
Ist Teil von
CA: a cancer journal for clinicians, 2018-07, Vol.68 (4), p.284-296
Ort / Verlag
United States: Wiley Subscription Services, Inc
Erscheinungsjahr
2018
Link zum Volltext
Quelle
Wiley Online Library Journals Frontfile Complete
Beschreibungen/Notizen
In 2018, there will be approximately 22,240 new cases of ovarian cancer diagnosed and 14,070 ovarian cancer deaths in the United States. Herein, the American Cancer Society provides an overview of ovarian cancer occurrence based on incidence data from nationwide population‐based cancer registries and mortality data from the National Center for Health Statistics. The status of early detection strategies is also reviewed. In the United States, the overall ovarian cancer incidence rate declined from 1985 (16.6 per 100,000) to 2014 (11.8 per 100,000) by 29% and the mortality rate declined between 1976 (10.0 per 100,000) and 2015 (6.7 per 100,000) by 33%. Ovarian cancer encompasses a heterogenous group of malignancies that vary in etiology, molecular biology, and numerous other characteristics. Ninety percent of ovarian cancers are epithelial, the most common being serous carcinoma, for which incidence is highest in non‐Hispanic whites (NHWs) (5.2 per 100,000) and lowest in non‐Hispanic blacks (NHBs) and Asians/Pacific Islanders (APIs) (3.4 per 100,000). Notably, however, APIs have the highest incidence of endometrioid and clear cell carcinomas, which occur at younger ages and help explain comparable epithelial cancer incidence for APIs and NHWs younger than 55 years. Most serous carcinomas are diagnosed at stage III (51%) or IV (29%), for which the 5‐year cause‐specific survival for patients diagnosed during 2007 through 2013 was 42% and 26%, respectively. For all stages of epithelial cancer combined, 5‐year survival is highest in APIs (57%) and lowest in NHBs (35%), who have the lowest survival for almost every stage of diagnosis across cancer subtypes. Moreover, survival has plateaued in NHBs for decades despite increasing in NHWs, from 40% for cases diagnosed during 1992 through 1994 to 47% during 2007 through 2013. Progress in reducing ovarian cancer incidence and mortality can be accelerated by reducing racial disparities and furthering knowledge of etiology and tumorigenesis to facilitate strategies for prevention and early detection. CA Cancer J Clin 2018;68:284–296. © 2018 American Cancer Society.
Sprache
Englisch
Identifikatoren
ISSN: 0007-9235
eISSN: 1542-4863
DOI: 10.3322/caac.21456
Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6621554
Format
–
Schlagworte
Adult
,
Aged
,
Aged, 80 and over
,
American Cancer Society
,
Carcinoma
,
Carcinoma - diagnosis
,
Carcinoma - epidemiology
,
Disease prevention
,
Early Detection of Cancer
,
epidemiology
,
epithelial ovarian cancers
,
Etiology
,
Female
,
health disparities
,
Health Status Disparities
,
Humans
,
Incidence
,
Medical diagnosis
,
Middle Aged
,
Mortality
,
Ovarian cancer
,
ovarian neoplasms
,
Ovarian Neoplasms - diagnosis
,
Ovarian Neoplasms - epidemiology
,
Prognosis
,
Statistics
,
Tumorigenesis
,
United States - epidemiology
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