The New England journal of medicine, 2019-05, Vol.380 (20), p.1918-1928
- Steers, Nicholas J
- Li, Yifu
- Drace, Zahida
- D’Addario, Justin A
- Fischman, Clara
- Liu, Lili
- Xu, Katherine
- Na, Young-Ji
- Neugut, Y. Dana
- Zhang, Jun Y
- Sterken, Roel
- Balderes, Olivia
- Bradbury, Drew
- Ozturk, Nilgun
- Ozay, Fatih
- Goswami, Sanya
- Mehl, Karla
- Wold, Jaclyn
- Jelloul, Fatima Z
- Rohanizadegan, Mersedeh
- Gillies, Christopher E
- Vasilescu, Elena-Rodica M
- Vlad, George
- Ko, Yi-An
- Mohan, Sumit
- Radhakrishnan, Jai
- Cohen, David J
- Ratner, Lloyd E
- Scolari, Francesco
- Susztak, Katalin
- Sampson, Matthew G
- Deaglio, Silvia
- Caliskan, Yasar
- Barasch, Jonathan
- Courtney, Aisling E
- Maxwell, Alexander P
- McKnight, Amy J
- Ionita-Laza, Iuliana
- Bakker, Stephan J.L
- Snieder, Harold
- de Borst, Martin H
- D’Agati, Vivette
- Amoroso, Antonio
- Gharavi, Ali G
- Kiryluk, Krzysztof
2019
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Details
- Autor(en) / Beteiligte
- Steers, Nicholas J
- Li, Yifu
- Drace, Zahida
- D’Addario, Justin A
- Fischman, Clara
- Liu, Lili
- Xu, Katherine
- Na, Young-Ji
- Neugut, Y. Dana
- Zhang, Jun Y
- Sterken, Roel
- Balderes, Olivia
- Bradbury, Drew
- Ozturk, Nilgun
- Ozay, Fatih
- Goswami, Sanya
- Mehl, Karla
- Wold, Jaclyn
- Jelloul, Fatima Z
- Rohanizadegan, Mersedeh
- Gillies, Christopher E
- Vasilescu, Elena-Rodica M
- Vlad, George
- Ko, Yi-An
- Mohan, Sumit
- Radhakrishnan, Jai
- Cohen, David J
- Ratner, Lloyd E
- Scolari, Francesco
- Susztak, Katalin
- Sampson, Matthew G
- Deaglio, Silvia
- Caliskan, Yasar
- Barasch, Jonathan
- Courtney, Aisling E
- Maxwell, Alexander P
- McKnight, Amy J
- Ionita-Laza, Iuliana
- Bakker, Stephan J.L
- Snieder, Harold
- de Borst, Martin H
- D’Agati, Vivette
- Amoroso, Antonio
- Gharavi, Ali G
- Kiryluk, Krzysztof
- Titel
- Genomic Mismatch at LIMS1 Locus and Kidney Allograft Rejection
- Ist Teil von
- The New England journal of medicine, 2019-05, Vol.380 (20), p.1918-1928
- Ort / Verlag
- United States: Massachusetts Medical Society
- Erscheinungsjahr
- 2019
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- This study explored gene-disrupting variants as risk factors for allosensitization in kidney transplant recipients. Genomic collision at the LIMS1 locus, which encodes a minor histocompatibility antigen, was associated with allograft rejection and production of anti-LIMS1 IgG2 and IgG3.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0028-4793eISSN: 1533-4406DOI: 10.1056/NEJMoa1803731Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6589355
- Format
- –
- Schlagworte
- Adaptor Proteins, Signal Transducing - genetics, Adaptor Proteins, Signal Transducing - immunology, Alloantibodies, Antibody response, Antigens, Cohort Studies, DNA Copy Number Variations, Gene deletion, Genes, Genetic Association Studies, Genomes, Genotype, Genotype & phenotype, Graft rejection, Graft Rejection - genetics, Grants, Heredity, Histocompatibility Testing, HLA Antigens - genetics, Humans, Immunoglobulin G, Immunoglobulin G - blood, Immunoglobulins, Kidney Transplantation, LIM Domain Proteins - genetics, LIM Domain Proteins - immunology, Membrane Proteins - genetics, Membrane Proteins - immunology, Minor histocompatibility antigens, Minority & ethnic groups, Polymorphism, Single Nucleotide, Protein arrays, Surgeons, Tissue Donors, Transplants & implants