American journal of infection control, 2016-07, Vol.44 (7), p.830-836
2016
Details
- Autor(en) / Beteiligte
- Titel
- Intestinal microbiome disruption in patients in a long-term acute care hospital: A case for development of microbiome disruption indices to improve infection prevention
- Ist Teil von
- American journal of infection control, 2016-07, Vol.44 (7), p.830-836
- Ort / Verlag
- United States: Elsevier Inc
- Erscheinungsjahr
- 2016
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Highlights • Antibiotic exposure was inversely correlated with intestinal microbiome diversity. • Diversity was lower in patients who received third- or fourth-generation cephalosporins. • Charlson Comorbidity Index score was inversely correlated with microbiome diversity. • Directly measuring microbiome disruption might be most predictive of adverse events. • Microbiome disruption indices have the potential to improve infection control efforts.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0196-6553eISSN: 1527-3296DOI: 10.1016/j.ajic.2016.01.003Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6538413
- Format
- –
- Schlagworte
- Adult, Aged, antibiotic use, Bacteria - classification, Bacteria - genetics, carbapenem-resistant Enterobacteriaceae, Clostridium difficile, Cluster Analysis, Cross-Sectional Studies, Diarrhea - microbiology, DNA, Bacterial - chemistry, DNA, Bacterial - genetics, DNA, Ribosomal - chemistry, DNA, Ribosomal - genetics, Fecal Microbiota Transplantation, Feces - microbiology, Female, Gastrointestinal Microbiome, Hospitals, Humans, Infection Control, Infectious Disease, intestinal microbiome, long-term acute care, Long-Term Care, Male, Microbiota, Middle Aged, Phylogeny, Pilot Projects, RNA, Ribosomal, 16S - genetics, Sequence Analysis, DNA, vancomycin-resistant enterococci