Details

Autor(en) / Beteiligte

• Cheng, Ying
• Mück‐Lichtenfeld, Christian
• Studer, Armido

Titel

Metal‐Free Radical Borylation of Alkyl and Aryl Iodides

Ist Teil von

• Angewandte Chemie (International ed.), 2018-12, Vol.57 (51), p.16832-16836

Auflage

International ed. in English

Ort / Verlag

Germany: Wiley Subscription Services, Inc

Erscheinungsjahr

2018

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A metal‐free radical borylation of alkyl and aryl iodides with bis(catecholato)diboron (B2cat2) as the boron source under mild conditions is introduced. The borylation reaction is operationally easy to conduct and shows high functional group tolerance and broad substrate scope. Radical clock experiments and density functional theory calculations provide insights into the mechanism and rate constants for C‐radical borylation with B2cat2 are disclosed. I to B: A metal and additive‐free radical borylation using a commercial diboron reagent is introduced. Alkyl and aryl iodides are borylated under very mild conditions in good to excellent yields.