The New England journal of medicine, 2018-12, Vol.379 (26), p.2506-2516
- Girard, Timothy D
- Exline, Matthew C
- Carson, Shannon S
- Hough, Catherine L
- Rock, Peter
- Gong, Michelle N
- Douglas, Ivor S
- Malhotra, Atul
- Owens, Robert L
- Feinstein, Daniel J
- Khan, Babar
- Pisani, Margaret A
- Hyzy, Robert C
- Schmidt, Gregory A
- Schweickert, William D
- Hite, R. Duncan
- Bowton, David L
- Masica, Andrew L
- Thompson, Jennifer L
- Chandrasekhar, Rameela
- Pun, Brenda T
- Strength, Cayce
- Boehm, Leanne M
- Jackson, James C
- Pandharipande, Pratik P
- Brummel, Nathan E
- Hughes, Christopher G
- Patel, Mayur B
- Stollings, Joanna L
- Bernard, Gordon R
- Dittus, Robert S
- Ely, E. Wesley
2018
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Girard, Timothy D
- Exline, Matthew C
- Carson, Shannon S
- Hough, Catherine L
- Rock, Peter
- Gong, Michelle N
- Douglas, Ivor S
- Malhotra, Atul
- Owens, Robert L
- Feinstein, Daniel J
- Khan, Babar
- Pisani, Margaret A
- Hyzy, Robert C
- Schmidt, Gregory A
- Schweickert, William D
- Hite, R. Duncan
- Bowton, David L
- Masica, Andrew L
- Thompson, Jennifer L
- Chandrasekhar, Rameela
- Pun, Brenda T
- Strength, Cayce
- Boehm, Leanne M
- Jackson, James C
- Pandharipande, Pratik P
- Brummel, Nathan E
- Hughes, Christopher G
- Patel, Mayur B
- Stollings, Joanna L
- Bernard, Gordon R
- Dittus, Robert S
- Ely, E. Wesley
- Titel
- Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness
- Ist Teil von
- The New England journal of medicine, 2018-12, Vol.379 (26), p.2506-2516
- Ort / Verlag
- United States: Massachusetts Medical Society
- Erscheinungsjahr
- 2018
- Quelle
- Free E-Journal (出版社公開部分のみ）
- Beschreibungen/Notizen
- In a multicenter trial in 566 patients with critical illness who had delirium, the use of haloperidol or ziprasidone, as compared with placebo, had no significant effect on the duration of delirium or coma. Side effects and extrapyramidal disorders occurred at similar rates in all groups.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0028-4793eISSN: 1533-4406DOI: 10.1056/NEJMoa1808217Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6364999
- Format
- –
- Schlagworte
- Aged, Antipsychotic Agents - adverse effects, Antipsychotic Agents - therapeutic use, Antipsychotics, Clinical trials, Cognitive ability, Coma, Critical Illness - mortality, Critical Illness - psychology, Critical Illness - therapy, Delirium, Delirium - drug therapy, Dopamine Antagonists - therapeutic use, Double-Blind Method, Double-blind studies, Drug dosages, Extrapyramidal system, FDA approval, Female, Haloperidol, Haloperidol - administration & dosage, Haloperidol - adverse effects, Haloperidol - therapeutic use, Humans, Illnesses, Informed consent, Intravenous administration, Kaplan-Meier Estimate, Male, Mechanical ventilation, Middle Aged, Patients, Piperazines - administration & dosage, Piperazines - adverse effects, Piperazines - therapeutic use, Psychotropic drugs, Respiratory failure, Respiratory Insufficiency - psychology, Shock - psychology, Thiazoles - administration & dosage, Thiazoles - adverse effects, Thiazoles - therapeutic use, Treatment Failure, Ventilators, Ziprasidone