Details

Autor(en) / Beteiligte

• Perazella, Mark A

Titel

Pharmacology behind Common Drug Nephrotoxicities

Ist Teil von

• Clinical journal of the American Society of Nephrology, 2018-12, Vol.13 (12), p.1897-1908

Ort / Verlag

United States: American Society of Nephrology

Erscheinungsjahr

2018

Quelle

MEDLINE

Beschreibungen/Notizen

• Patients are exposed to numerous prescribed and over-the-counter medications. Unfortunately, drugs remain a relatively common cause of acute and chronic kidney injury. A combination of factors including the innate nephrotoxicity of drugs, underlying patient characteristics that increase their risk for kidney injury, and the metabolism and pathway of excretion by the kidneys of the various agents administered enhance risk for drug-induced nephrotoxicity. This paper will review these clinically relevant aspects of drug-induced nephrotoxicity for the clinical nephrologist.