Details

Autor(en) / Beteiligte

• Khan, Yasser
• Han, Donggeon
• Pierre, Adrien
• Ting, Jonathan
• Wang, Xingchun
• Lochner, Claire M.
• Bovo, Gianluca
• Yaacobi-Gross, Nir
• Newsome, Chris
• Wilson, Richard
• Arias, Ana C.

Titel

A flexible organic reflectance oximeter array

Ist Teil von

• Proceedings of the National Academy of Sciences - PNAS, 2018-11, Vol.115 (47), p.E11015-E11024

Ort / Verlag

United States: National Academy of Sciences

Erscheinungsjahr

2018

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Transmission-mode pulse oximetry, the optical method for determining oxygen saturation in blood, is limited to only tissues that can be transilluminated, such as the earlobes and the fingers. The existing sensor configuration provides only singlepoint measurements, lacking 2D oxygenation mapping capability. Here, we demonstrate a flexible and printed sensor array composed of organic light-emitting diodes and organic photodiodes, which senses reflected light from tissue to determine the oxygen saturation. We use the reflectance oximeter array beyond the conventional sensing locations. The sensor is implemented to measure oxygen saturation on the forehead with 1.1% mean error and to create 2D oxygenation maps of adult forearms under pressure-cuff–induced ischemia. In addition, we present mathematical models to determine oxygenation in the presence and absence of a pulsatile arterial blood signal. The mechanical flexibility, 2D oxygenation mapping capability, and the ability to place the sensor in various locations make the reflectance oximeter array promising for medical sensing applications such as monitoring of real-time chronic medical conditions as well as postsurgery recovery management of tissues, organs, and wounds.