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ACCELEROMETER PHYSICAL ACTIVITY AND SEDENTARY BEHAVIOR AND MORTALITY RISK IN OLDER WOMEN: THE OPACH STUDY
Ist Teil von
Innovation in aging, 2017-07, Vol.1 (suppl_1), p.1184-1185
Ort / Verlag
US: Oxford University Press
Erscheinungsjahr
2017
Quelle
EZB Free E-Journals
Beschreibungen/Notizen
The consistently observed associations for self-reported physical activity (PA) and sedentary behavior (SB) with mortality may be underestimated by exposure measurement error, especially in older adults. We examined accelerometer measured PA and SB with all-cause mortality in 6,385 women ages 63–91 followed a mean of 2.5 years. Vector magnitude counts/15-sec epoch from hip worn triaxial accelerometers (required ≥4 of 7 days with ≥10 hr/day wear time) were used to define time in SB (0–18 counts/15 sec) and total PA (≥19 counts/15 sec; all intensities combined) based on cutpoints determined from a calibration study among similarly aged women. Cox regression was used to estimate hazard ratios (HR) and 95% confidence intervals (CI) for these associations. There were 271 (4.2%) deaths during 14,212 person-years follow-up. An inverse gradient in mortality rates was observed across incremental PA quartiles: 38.2, 16.5, 13.9, 8.5 per 1,000 person-years (trend, p<.001). Adjusting for accelerometer wear-time, age, and race, corresponding HRs (CI) for PA quartiles were 1.00 (referent), 0.50 (0.37–0.69), 0.52 (0.37–0.73), 0.36 (0.24–0.54), trend p<.001. Mortality rates for incremental SB quartiles were 10.5, 13.8, 23.1, and 29.3 per 1,000 person-years (p<.001). Corresponding adjusted HRs (CI) for SB quartiles were 1.00 (referent), 1.19 (0.78–1.82), 1.90 (1.29–2.81), 2.25 (1.53–3.33), trend p<.001. Preliminary additional adjustments for smoking, alcohol, comorbidities and measured physical functioning did not substantively change the pattern of association with mortality for PA or SB. Total PA and SB measured by accelerometry are associated with mortality in older women. Intervening on both behaviors could improve longevity at older ages.