Details

Autor(en) / Beteiligte

• Edens, Cuoghi
• Rodrigues, Bruna Costa
• Lacerda, Marcela Ignacchiti
• Dos Santos, Flavia Cunha
• De Jesús, Guilherme R
• De Jesús, Nilson Ramires
• Levy, Roger A
• Leatherwood, Cianna
• Mandel, Jess
• Bermas, Bonnie

Titel

Challenging cases in rheumatic pregnancies

Ist Teil von

• Rheumatology (Oxford, England), 2018-07, Vol.57 (suppl_5), p.v18-v25

Ort / Verlag

England: Oxford University Press

Erscheinungsjahr

2018

Quelle

Oxford Journals 2020 Medicine

Beschreibungen/Notizen

• Abstract This article describes three complicated cases in rheumatology and pregnancy. The first case elucidates the challenges in treating SLE in conjunction with pulmonary arterial hypertension, while the second case features an SLE-affected pregnancy with development of portal hypertension secondary to portal vein thrombosis related to APS. The third case is a pregnant woman with stable SLE who developed thrombotic microangiopathy caused by atypical haemolytic uraemic syndrome, and failed to improve despite multiple measures including biopsy and elective preterm delivery. There are grave and unique challenges for women with autoimmune disease, but adverse outcomes can sometimes be avoided with careful and multidisciplinary medical management. Pre-conception counselling with regard to medications and disease treatment should also include discussion of the advisability of pregnancy, which may be difficult for a patient, but present the best course for optimizing health outcomes.