Details

Autor(en) / Beteiligte

• Kouijzer, Ilse J. E.
• Scheper, Henk
• de Rooy, Jacky W. J.
• Bloem, Johan L.
• Janssen, Marcel J. R.
• van den Hoven, Leon
• Hosman, Allard J. F.
• Visser, Leo G.
• Oyen, Wim J. G.
• Bleeker-Rovers, Chantal P.
• de Geus-Oei, Lioe-Fee

Titel

The diagnostic value of 18F–FDG-PET/CT and MRI in suspected vertebral osteomyelitis – a prospective study

Ist Teil von

• European journal of nuclear medicine and molecular imaging, 2018-05, Vol.45 (5), p.798-805

Ort / Verlag

Berlin/Heidelberg: Springer Berlin Heidelberg

Erscheinungsjahr

2018

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Purpose The aim of this study was to determine the diagnostic value of 18 F–fluorodeoxyglucose (FDG) positron emission tomography and computed tomography (PET/CT) and magnetic resonance imaging (MRI) in diagnosing vertebral osteomyelitis. Methods From November 2015 until December 2016, 32 patients with suspected vertebral osteomyelitis were prospectively included. All patients underwent both 18 F–FDG-PET/CT and MRI within 48 h. All images were independently reevaluated by two radiologists and two nuclear medicine physicians who were blinded to each others’ image interpretation. 18 F–FDG-PET/CT and MRI were compared to the clinical diagnosis according to international guidelines. Results For 18 F–FDG-PET/CT, sensitivity, specificity, PPV, and NPV in diagnosing vertebral osteomyelitis were 100%, 83.3%, 90.9%, and 100%, respectively. For MRI, sensitivity, specificity, PPV, and NPV were 100%, 91.7%, 95.2%, and 100%, respectively. MRI detected more epidural/spinal abscesses. An important advantage of 18 F–FDG-PET/CT is the detection of metastatic infection (16 patients, 50.0%). Conclusion 18 F–FDG-PET/CT and MRI are both necessary techniques in diagnosing vertebral osteomyelitis. An important advantage of 18 F–FDG-PET/CT is the visualization of metastatic infection, especially in patients with bacteremia. MRI is more sensitive in detection of small epidural abscesses.