Details

Autor(en) / Beteiligte

• Chen, Linlin
• Deng, Huidan
• Cui, Hengmin
• Fang, Jing
• Zuo, Zhicai
• Deng, Junliang
• Li, Yinglun
• Wang, Xun
• Zhao, Ling

Titel

Inflammatory responses and inflammation-associated diseases in organs

Ist Teil von

• Oncotarget, 2018-01, Vol.9 (6), p.7204-7218

Ort / Verlag

United States: Impact Journals LLC

Erscheinungsjahr

2018

Link zum Volltext

Quelle

Electronic Journals Library

Beschreibungen/Notizen

• Inflammation is a biological response of the immune system that can be triggered by a variety of factors, including pathogens, damaged cells and toxic compounds. These factors may induce acute and/or chronic inflammatory responses in the heart, pancreas, liver, kidney, lung, brain, intestinal tract and reproductive system, potentially leading to tissue damage or disease. Both infectious and non-infectious agents and cell damage activate inflammatory cells and trigger inflammatory signaling pathways, most commonly the NF-κB, MAPK, and JAK-STAT pathways. Here, we review inflammatory responses within organs, focusing on the etiology of inflammation, inflammatory response mechanisms, resolution of inflammation, and organ-specific inflammatory responses.