Details

Autor(en) / Beteiligte

• Ataide, Janaína Artem
• de Carvalho, Nathália Mendes
• Rebelo, Márcia de Araújo
• Chaud, Marco Vinícius
• Grotto, Denise
• Gerenutti, Marli
• Rai, Mahendra
• Mazzola, Priscila Gava
• Jozala, Angela Faustino

Titel

Bacterial Nanocellulose Loaded with Bromelain: Assessment of Antimicrobial, Antioxidant and Physical-Chemical Properties

Ist Teil von

• Scientific reports, 2017-12, Vol.7 (1), p.18031-18031, Article 18031

Ort / Verlag

England: Nature Publishing Group

Erscheinungsjahr

2017

Quelle

Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals

Beschreibungen/Notizen

• Bacterial nanocellulose (BNC) has desirable properties for wound healing such as high purity, good shape retention, and high water binding capacity. Bromelain is a protease found in pineapple tissues and has been applied in several fields, it has anti-inflammatory and anticancer properties, promotes cell apoptosis, amongst others. In this work, a BNC based device for the controlled release of bromelain was developed. BNC were submersed in sterilized bromelain solution and incubated at 25 °C under 100 rpm for 24 h. Physical-chemical properties, protein concentration, antioxidant and antimicrobial activities were measured. Results demonstrate that BNC could improve bromelain antimicrobial activity 9 times. Those findings allow concluding that bromelain is a promising molecule to be incorporated into BNC's. The BNC's characteristics seem to represent a new promising delivery system of the loaded biomolecule, and protected from external actions.