Details

Autor(en) / Beteiligte

• Sumanasuriya, S
• Lambros, MB
• Bono, JS

Titel

Application of Liquid Biopsies in Cancer Targeted Therapy

Ist Teil von

• Clinical pharmacology and therapeutics, 2017-11, Vol.102 (5), p.745-747

Ort / Verlag

United States: John Wiley and Sons Inc

Erscheinungsjahr

2017

Quelle

Wiley Online Library Journals Frontfile Complete

Beschreibungen/Notizen

• As a growing body of evidence demonstrates intertumoral and intratumoral heterogeneity and clonal evolution, both during carcinogenesis and also throughout treatment resulting in acquired drug resistance, the utility of blood‐based assays or “liquid biopsies” is becoming increasingly recognized in clinical practice and trial design. “Liquid biopsies” provide a less invasive approach to the current gold standard of interrogating tumors by tissue biopsies, which are frequently unfeasible, associated with morbidity, and cannot be performed as often.