Details

Autor(en) / Beteiligte

• Liesman, Rachael M
• Pritt, Bobbi S
• Maleszewski, Joseph J
• Patel, Robin
• Kraft, Colleen Suzanne

Titel

Laboratory Diagnosis of Infective Endocarditis

Ist Teil von

• Journal of clinical microbiology, 2017-09, Vol.55 (9), p.2599-2608

Ort / Verlag

United States: American Society for Microbiology

Erscheinungsjahr

2017

Quelle

MEDLINE

Beschreibungen/Notizen

• Infective endocarditis is life-threatening; identification of the underlying etiology informs optimized individual patient management. Changing epidemiology, advances in blood culture techniques, and new diagnostics guide the application of laboratory testing for diagnosis of endocarditis. Blood cultures remain the standard test for microbial diagnosis, with directed serological testing (i.e., Q fever serology, serology) in culture-negative cases. Histopathology and molecular diagnostics (e.g., 16S rRNA gene PCR/sequencing, PCR) may be applied to resected valves to aid in diagnosis. Herein, we summarize recent knowledge in this area and propose a microbiologic and pathological algorithm for endocarditis diagnosis.