Details

Autor(en) / Beteiligte

• Phuong, Pham Cam
• Nam, LE Viet
• Schild, Steven E
• Rades, Dirk
• Khoa, Mai Trong

Titel

A Survival Score Based on Symptoms and Performance Status for Patients with High-grade Gliomas Receiving Radiochemotherapy

Ist Teil von

• In vivo (Athens), 2017-07, Vol.31 (4), p.689-693

Ort / Verlag

Greece: International Institute of Anticancer Research

Erscheinungsjahr

2017

Quelle

MEDLINE

Beschreibungen/Notizen

• To create a simple survival score for patients with high-grade gliomas based on clinical symptoms and performance status. Thirty-six patients received neurosurgical intervention followed by radiochemotherapy for high-grade gliomas. Six pre-treatment symptoms were included in the score depending on their impairment of quality of life, scoring each between 1 and 3. For each patient, the points from the symptoms were added and another 4 points were added for Karnofsky performance status (KPS) <80%. Based on the survival rates of these scores, two groups were formed: 1-4 (group A) and 5-12 points (group B). The 1-, 2- and 3-year survival rates in group A were 100%, 33% and 24% in group A and 47%, 7% and 0% in group B (p<0.001). In addition, complete tumor resection (p<0.001) and tumor grade III (p<0.001) were associated with improved survival. A simple survival score was developed helping physicians in decision-making for patients with high-grade gliomas.