Details

Autor(en) / Beteiligte

• Gudiol, Carlota
• Royo-Cebrecos, Cristina
• Abdala, Edson
• Akova, Murat
• Álvarez, Rocío
• Maestro-de la Calle, Guillermo
• Cano, Angela
• Cervera, Carlos
• Clemente, Wanessa T
• Martín-Dávila, Pilar
• Freifeld, Alison
• Gómez, Lucía
• Gottlieb, Thomas
• Gurguí, Mercè
• Herrera, Fabián
• Manzur, Adriana
• Maschmeyer, Georg
• Meije, Yolanda
• Montejo, Miguel
• Peghin, Maddalena
• Rodríguez-Baño, Jesús
• Ruiz-Camps, Isabel
• Sukiennik, Teresa C
• Tebe, Cristian
• Carratalà, Jordi

Titel

Efficacy of β-Lactam/β-Lactamase Inhibitor Combinations for the Treatment of Bloodstream Infection Due to Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae in Hematological Patients with Neutropenia

Ist Teil von

• Antimicrobial agents and chemotherapy, 2017-08, Vol.61 (8)

Ort / Verlag

United States: American Society for Microbiology

Erscheinungsjahr

2017

Quelle

MEDLINE

Beschreibungen/Notizen

• β-Lactam/β-lactamase inhibitors (BLBLIs) were compared to carbapenems in two cohorts of hematological neutropenic patients with extended-spectrum-β-lactamase (ESBL) bloodstream infection (BSI): the empirical therapy cohort (174 patients) and the definitive therapy cohort (251 patients). The 30-day case fatality rates and other secondary outcomes were similar in the two therapy groups of the two cohorts and also in the propensity-matched cohorts. BLBLIs might be carbapenem-sparing alternatives for the treatment of BSI due to ESBLs in these patients.