Details

Autor(en) / Beteiligte

• Dohi, Kenji
• Satoh, Kazue
• Miyamoto, Kazuyuki
• Momma, Shusuke
• Fukuda, Kenichiro
• Higuchi, Ryo
• Ohtaki, Hirokazu
• Banks, Williams A

Titel

Molecular hydrogen in the treatment of acute and chronic neurological conditions: mechanisms of protection and routes of administration

Ist Teil von

• Journal of Clinical Biochemistry and Nutrition, 2017, Vol.61(1), pp.1-5

Ort / Verlag

Japan: SOCIETY FOR FREE RADICAL RESEARCH JAPAN

Erscheinungsjahr

2017

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Oxidative stress caused by reactive oxygen species is considered a major mediator of tissue and cell injuries in various neuronal conditions, including neurological emergencies and neurodegenerative diseases. Molecular hydrogen is well characterized as a scavenger of hydroxyl radicals and peroxynitrite. Recently, the neuroprotective effects of treatment with molecular hydrogen have been reported in both basic and clinical settings. Here, we review the effects of hydrogen therapy in acute neuronal conditions and neurodegenerative diseases. Hydrogen therapy administered in drinking water may be useful for the prevention of neurodegenerative diseases and for reducing the symptoms of acute neuronal conditions.