Journal of biomedical research, 2017-01, Vol.31 (2), p.122-129
2017
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- Autor(en) / Beteiligte
- Titel
- Comparative effects of plant oils and trans-fat on blood lipid profiles and ischemic stroke in rats
- Ist Teil von
- Journal of biomedical research, 2017-01, Vol.31 (2), p.122-129
- Ort / Verlag
- China: Editorial Department of Journal of Biomedical Research
- Erscheinungsjahr
- 2017
- Quelle
- EZB-FREE-00999 freely available EZB journals
- Beschreibungen/Notizen
- Since plant oils are believed to be better than animal fats for cerebrovascular and cardiovascular diseases, the effects of various plant oils and trans-fat on blood lipid profiles and ischemic stroke were investigated. Sprague- Dawley rats were fed a diet containing the oils or trans-fat, and then body weights, blood lipids, and effects on brain infarction and physical dysfunction induced by middle cerebral artery occlusion （MCAO） were analyzed. All the oils and trans-fat, except perilla oil, significantly increased body fats and body weight gain. Sesame oil and trans-fat specifically increased blood cholesterols and triglycerides, respectively, while perilla oil decreased both cholesterols and triglycerides. Perilla oil not only attenuated cerebral infarction, but also restored locomotor activity and rota-rod performances of MCAO rats. It is suggested that perilla oil among oils and fats could be the first choice to reduce the risk of metabolic syndrome and ischemic stroke.