Details

Autor(en) / Beteiligte

• Hoberman, Alejandro
• Paradise, Jack L
• Rockette, Howard E
• Kearney, Diana H
• Bhatnagar, Sonika
• Shope, Timothy R
• Martin, Judith M
• Kurs-Lasky, Marcia
• Copelli, Susan J
• Colborn, D. Kathleen
• Block, Stan L
• Labella, John J
• Lynch, Thomas G
• Cohen, Norman L
• Haralam, MaryAnn
• Pope, Marcia A
• Nagg, Jennifer P
• Green, Michael D
• Shaikh, Nader

Titel

Shortened Antimicrobial Treatment for Acute Otitis Media in Young Children

Ist Teil von

• The New England journal of medicine, 2016-12, Vol.375 (25), p.2446-2456

Ort / Verlag

United States: Massachusetts Medical Society

Erscheinungsjahr

2016

Link zum Volltext

Quelle

EZB-FREE-00999 freely available EZB journals

Beschreibungen/Notizen

• In children 6 to 23 months of age with otitis media, 5 days of antibiotic therapy was associated with less-favorable outcomes than standard 10-day treatment. The shorter course did not result in a lower rate of adverse events or of emergence of antimicrobial resistance. Next to the common cold, acute otitis media is the most frequently diagnosed illness in children in the United States 1 and the most commonly cited indication for antimicrobial treatment. 2 Concerns about the possible encouragement of antimicrobial resistance have led to recommendations by some clinicians that antimicrobial agents be withheld in large subgroups of children with acute otitis media, unless symptoms persist or worsen. 3 However, two trials lend support for routine antimicrobial treatment in young children, because affected participants younger than 3 years of age who received antimicrobial treatment for 7 or 10 days had more favorable outcomes than those who . . .