General and comparative endocrinology, 2017-03, Vol.243, p.60-69
2017
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Details
- Autor(en) / Beteiligte
- Titel
- Exogenous iodide ameliorates perchlorate-induced thyroid phenotypes in threespine stickleback
- Ist Teil von
- General and comparative endocrinology, 2017-03, Vol.243, p.60-69
- Ort / Verlag
- United States: Elsevier Inc
- Erscheinungsjahr
- 2017
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Highlights • Exogenous iodide ameliorates perchlorate-induced phenotypes in the thyroid. • Exogenous thyroxine partially ameliorates perchlorate-induced thyroid phenotypes. • NIS interference likely mediates perchlorate’s mode of action at the thyroid. • Perchlorate induces lipid droplet proliferation around subadult thyroid follicles. • Perchlorate may act as an obesogen in reproductively immature fish.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0016-6480eISSN: 1095-6840DOI: 10.1016/j.ygcen.2016.10.014Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5318228
- Format
- –
- Schlagworte
- Animals, Endocrine disruption, Endocrinology & Metabolism, Histopathology, Iodides - pharmacology, NIS, Obesogen, Perchlorates - toxicity, Phenotype, Sexual Maturation - drug effects, Smegmamorpha, Sodium-iodide symporter, Thyroid Dysgenesis - chemically induced, Thyroid Dysgenesis - prevention & control, Thyroid Epithelial Cells - drug effects, Thyroid Gland - drug effects, Thyroxine, Thyroxine - pharmacology