Details

Autor(en) / Beteiligte

• Weiss, Robert A.
• McDaniel, David H.
• Weiss, Margaret A.
• Mahoney, Anne Marie
• Beasley, Karen L.
• Halvorson, Christian R.

Titel

Safety and efficacy of a novel diffractive lens array using a picosecond 755 nm alexandrite laser for treatment of wrinkles

Ist Teil von

• Lasers in surgery and medicine, 2017-01, Vol.49 (1), p.40-44

Ort / Verlag

United States: John Wiley and Sons Inc

Erscheinungsjahr

2017

Link zum Volltext

Quelle

Wiley Online Library - AutoHoldings Journals

Beschreibungen/Notizen

• Introduction Picosecond lasers have been reported to be effective for removal of tattoo pigment. This prospective study evaluated the efficacy and safety of the treatment of peri‐oral and ‐ocular wrinkles using a novel diffractive lens array coupled with a picosecond 755 nm alexandrite laser. Methods Forty female subjects presenting with wrinkles from photodamage were enrolled in an IRB approved study. Subjects received four picosecond diffractive lens array treatments to the full face at 1 month intervals. Six subjects were biopsied (two subjects at 1 month, two subjects at 3 months, and two subjects at 6 months). Digital photographic images were taken at 1, 3, and 6 months post‐final treatment visits. Images were graded by blinded physicians for fine lines/wrinkles, erythema, dyschromia, and global improvement. Data on discomfort level, satisfaction, and side effects were recorded. Results Overall blinded physician rated global improvement ranged from improved to much improved at 1‐, 3‐, and 6‐month time points. At baseline the average Fitzpatrick wrinkle score was 5.48. At the 6‐month follow‐up the average score was 3.47. The overall average change in score from pre‐treatment to post‐treatment was 1.97. Subject self‐assessment at 6 months indicated that 90% of subjects were extremely or satisfied with their results. Unanticipated adverse events were absent with anticipated post‐treatment erythema lasting for just several hours. Conclusions A novel diffractive lens array used with a picosecond 755 nm alexandrite laser for treatment of wrinkles is highly effective and safe for wrinkles and other signs of photoaging. Lasers Surg. Med. 49:40–44, 2017. © 2016 The Authors. Lasers in Surgery and Medicine Published by Wiley Periodicals, Inc.